ABOUT THIS ROLE
Northreach are working with an innovative biotechnology company who are seeking a highly motivated Biomarker Development Scientist to work within the GCLP team, Translational Research. This position will report into the Senior Director, Translational Research.
The Biomarker Development Scientist will be responsible for developing and validating assays within the company GCLP Laboratory. These assays will be deployed to elucidate biomarker and immunogenicity profiles of new and existing clinical-stage gene therapies. The candidate should be proactive, inquisitive and a self-starter who is eager to learn and thrives in fast-paced environment.
The position will be based in central London and is laboratory-based.
- Develop, validate and troubleshoot immunoassays used to characterise clinical-stage gene therapies
- Provide scientific oversight of assays outsourced to contract research organisations
- Evaluate new assay technologies and other applications for improved performance and efficiency of laboratory activities
- Write and review SOPs and documents for the GCLP laboratory
- If required, assist with the analysis clinical samples following internal SOPs, working practices and policies
- Line management of laboratory-based scientists within the GCLP team
- Develop close and effective partnerships with other non-clinical and clinical scientists and project teams to foster a collaborative work environment
- Complete projects and prepare reports appropriate for internal or external partners
- Prepare presentations and represent research internally and externally
- Maintain awareness of current developments in the field through comprehensive reading of the literature and attendance at appropriate scientific meetings
THE IDEAL CANDIDATE
- Ph.D. in a Biological Science (e.g., Immunology, Biochemistry, Cell Biology, Bioanalytical or a related field) and at least 4 years of post-doctoral experience preferably within the biotech / pharmaceutical sector.
- Strong experience with bioanalytical method development, validation and troubleshooting of immunoassay techniques including multiplex approaches e.g. Luminex or MSD platforms and/or ADA assays.
- Experience of working with biological samples obtained from clinical trials.
- Demonstrate scientific creativity, critical thinking, and analytical problem-solving skills, with a strong track record of research productivity
- Experience of working in a GLP/GCP compliant environment is an advantage
- Strong scientific skills with the ability to collaborate with project team members.
- Excellent collaboration, communication, and decision-making skills.
- Ability to work within tight timelines when required
- An enthusiastic, innovative, data-driven scientist with a “can do” attitude